Integrin beta 2 anticorps

N° du produit ABIN6939823

L’anticorps anti-Integrin beta 2 Monoclonal Souris est utilisé pour la détection de Integrin beta 2 dans des échantillons de Humain. Il a été validé pour FACS, IF et Func.

Aperçu rapide pour Integrin beta 2 anticorps (ABIN6939823)

Antigène: Integrin beta 2 (ITGB2)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Integrin beta 2 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

Clone: 68-5A5

Détail du produit anti-Integrin beta 2 anticorps

Fonction: CD18 / Integrin beta-2 (ITGB2) Antibody

Specificité: Integrins are heterodimers composed of noncovalently associated transmembrane both receptor clustering and ligand occupancy are necessary for the activation of integrinmediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Stimulated human leukocytes

Isotype: IgG2a, kappa

Information d'application

Indications d'application:

Positive Control: Lymphocytes, granulocytes and macrophages in tonsil or lymph node.

Known Application: Functional Studies (Order Ab without Azide),Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Integrin beta 2

Antigène: Integrin beta 2 (ITGB2)

Autre désignation: ITGB2

Sujet:

Beta 2 (antigen CD18 (p95), CD18, Cell surface adhesion glycoproteins LFA 1/CR3/p150,95 subunit beta, Cell surface adhesion glycoproteins LFA-1/CR3/p150, Complement component 3 receptor 3 and 4 subunit, Complement receptor C3 beta subunit, Integrin beta-2 (ITGB2), LAD, LCAMB, Leukocyte Cell Adhesion Molecule CD18, Lymphocyte function associated antigen 1 (LFA1), MAC1, Macrophage antigen 1 (mac1) beta

granulocytes and macrophages in tonsil or lymph node., Lymphocytes

Poids moléculaire: 95kDa

ID gène: 3689, 375957

UniProt: P05107

Pathways: Signalisation NF-kappaB, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation