PMEPA1 anticorps

N° du produit ABIN6940417

Cet anticorps Souris Monoclonal détecte spécifiquement PMEPA1 dans IHC et StM. Il présente une réactivité envers Humain.

Aperçu rapide pour PMEPA1 anticorps (ABIN6940417)

Antigène: PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PMEPA1 est non-conjugé

Application: Immunohistochemistry (IHC), Staining Methods (StM)

Clone: PMEPA1-2696

Détail du produit anti-PMEPA1 anticorps

Purification: Purified by Protein A/G

Immunogène: Recombinant full-length human PMEPA1 protein

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: Human prostate, breast or renal cell carcinoma tissue (IHC).

Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur PMEPA1

Antigène: PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))

Autre désignation: PMEPA1

Sujet: PMEPA1 (prostate transmembrane protein, androgen induced 1 is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate, kidney and ovary, PMEPA1 interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels, specifically in prostate cells. Down regulation of PMEPA1 is observed in prostate tumors, suggesting that PMEPA1 may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer.

Poids moléculaire: 32kDa

ID gène: 56937

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway