STAT2 anticorps

N° du produit ABIN6940668

Cet anticorps anti-STAT2 Monoclonal Souris (Clone STAT2-2650) (ABIN6940668) détecte spécifiquement STAT2 dans IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour STAT2 anticorps (ABIN6940668)

Antigène: STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp STAT2 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: STAT2-2650

Détail du produit anti-STAT2 anticorps

Fonction: STAT2 Antibody

Specificité: Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of JAK kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN- is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 has been shown to be activated by prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant full-length human STAT2 protein

Isotype: IgG1, kappa

Information d'application

Indications d'application:

Positive Control: Ramos and Jurkat cell lysates. HeLa cell extract. Human lung carcinoma tissue.

Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur STAT2

Antigène: STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))

Autre désignation: STAT2

Sujet:

Homo sapiens interferon alpha induced transcriptional activator, interferon alpha induced transcriptional activator (ISGF3), P113, signal transducer and activator of transcription 2 113kD (STAT113), Signal transducer and activator of transcription 2 (STAT2)

Ramos and Jurkat cell lysates. HeLa cell extract. Human lung carcinoma tissue.

Poids moléculaire: 113kDa

ID gène: 6773, 530595

UniProt: P52630

Pathways: Signalistation JAK/STAT, Hepatitis C, CXCR4-mediated Signaling Events