TGFA anticorps (C-Term)

N° du produit ABIN6940716

L’anticorps Souris Monoclonal anti-TGFA a été validé pour IF et FACS. Il convient pour détecter TGFA dans des échantillons de Humain, Rat, Souris et Boeuf (Vache).

Aperçu rapide pour TGFA anticorps (C-Term) (ABIN6940716)

Antigène: TGFA (Transforming Growth Factor, alpha (TGFA))

Reactivité: Humain, Rat, Souris, Boeuf (Vache)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TGFA est non-conjugé

Application: Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: SPM357

Détail du produit anti-TGFA anticorps

Épitope: C-Term

Specificité: This antibody reacts with the C-terminus of TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. The staining with Ab-1 is completely blocked by the peptide used for raising this antibody. TGF (aa50) is a growth factor with 33 % homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.

Purification: Purified by Protein A/G

Immunogène: A 17-amino acid synthetic peptide from the carboxyl-terminus of rat TGFα.

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: Jurkat or Ramos cells. Testicular Carcinoma.

Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur TGFA

Antigène: TGFA (Transforming Growth Factor, alpha (TGFA))

Autre désignation: TGFA

Poids moléculaire: ~6kDa

ID gène: 7039

UniProt: P01135

Pathways: Signalisation NF-kappaB, Signalisation RTK, EGFR Signaling Pathway