YWHAE anticorps

N° du produit ABIN6940908

L’anticorps Souris Monoclonal anti-YWHAE a été validé pour WB, IHC et StM. Il convient pour détecter YWHAE dans des échantillons de Humain.

Aperçu rapide pour YWHAE anticorps (ABIN6940908)

Antigène: YWHAE (14-3-3 epsilon (YWHAE))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp YWHAE est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Staining Methods (StM)

Clone: CPTC-YWHAE-1

Détail du produit anti-YWHAE anticorps

Purification: Purified by Protein A/G

Immunogène: Recombinant human full-length YWHAE protein

Isotype: IgG2a kappa

Information d'application

Indications d'application:

Positive Control: HEK-293 or A-431 cell lines.

Known Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur YWHAE

Antigène: YWHAE (14-3-3 epsilon (YWHAE))

Autre désignation: YWHAE

Sujet: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. The YWHAE gene which encodes 14-3-3E has also been identified as a possible susceptibility gene for schizophrenia.

Poids moléculaire: 29.4kDa

ID gène: 7531

UniProt: P62268

Pathways: Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, M Phase