Cyclin E1 anticorps (AA 10-176)

N° du produit ABIN6940995

Cet anticorps Souris Monoclonal détecte spécifiquement Cyclin E1 dans ELISA et Coat. Il présente une réactivité envers Humain.

Aperçu rapide pour Cyclin E1 anticorps (AA 10-176) (ABIN6940995)

Antigène: Cyclin E1 (CCNE1)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cyclin E1 est non-conjugé

Application: ELISA, Coating (Coat)

Clone: CCNE1-2587

Détail du produit anti-Cyclin E1 anticorps

Épitope: AA 10-176

Purification: Purified by Protein A/G

Immunogène: Recombinant human Cyclin E (CCNE1) protein fragment (around aa 10-176) (exact sequence is proprietary)

Isotype: IgG kappa

Information d'application

Indications d'application:

Positive Control: HeLa cells. Breast or Colon Carcinoma.

Known Application: ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Cyclin E1

Antigène: Cyclin E1 (CCNE1)

Autre désignation: CCNE1

Sujet: Cyclin E belongs to the highly conserved cyclin family, whose members exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclins function as regulators of CDK kinases. Cyclin E forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. Cyclin E accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Cyclin E overexpression has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis.

Poids moléculaire: 53kDa

ID gène: 898

UniProt: P24864

Pathways: Cycle Cellulaire, Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Mitotic G1-G1/S Phases