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CD28 anticorps

CD28 Reactivité: Humain FACS, IF, Func Hôte: Souris Monoclonal CB28 unconjugated
N° du produit ABIN6941130
  • Antigène Voir toutes CD28 Anticorps
    CD28
    Reactivité
    • 182
    • 141
    • 61
    • 38
    • 21
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    • 12
    • 12
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    Humain
    Hôte
    • 144
    • 79
    • 39
    • 18
    • 8
    • 3
    • 2
    • 1
    Souris
    Clonalité
    • 214
    • 74
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    Monoclonal
    Conjugué
    • 97
    • 31
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    Cet anticorp CD28 est non-conjugé
    Application
    • 214
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    Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)
    Specificité
    Recognizes a glycoprotein of 44-88 kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.
    Purification
    Purified by Protein A/G
    Immunogène
    Recombinant human CD28 protein
    Clone
    CB28
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product CD28 Anticorps primaire
  • Indications d'application

    Positive Control: Jurkat cells. Human lymph nodes and tonsils.

    Known Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Functional Studies (Order Ab without BSA & Azide), ,Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Date de péremption
    24 months
  • Antigène
    CD28
    Autre désignation
    CD28 (CD28 Produits)
    Synonymes
    anticorps Tp44, anticorps CD28RNA, anticorps cd28, anticorps CD28 molecule, anticorps CD28 antigen, anticorps Cd28 molecule, anticorps CD28 molecule L homeolog, anticorps CD28, anticorps Cd28, anticorps cd28.L
    Poids moléculaire
    44kDa (monomer), 88kDa (dimer)
    ID gène
    940
    UniProt
    P10747
    Pathways
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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