Angiopoietin 2 anticorps (AA 200-350)
Aperçu rapide pour Angiopoietin 2 anticorps (AA 200-350) (ABIN6942114)
Antigène
Voir toutes Angiopoietin 2 (ANGPT2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Épitope
- AA 200-350
-
Fonction
- Angiopoietin 2 (4G2) Monoclonal Antibody
-
Réactivité croisée
- Humain, Souris, Rat
-
Purification
- Purified by Protein A.
-
Immunogène
- Human Angiopoietin 2 aa 200-350
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB(1:300-5000), IHC-P(1:200-400)
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- Lot specific
-
Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
Agent conservateur
- ProClin
-
Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
Date de péremption
- 12 months
-
-
- Angiopoietin 2 (ANGPT2)
-
Autre désignation
- ANGPT2
-
Sujet
-
Synonyms: Angiopoietin-2, ANG-2, ANGPT2.
Background: Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.
-
ID gène
- 285
-
UniProt
- O15123
-
Pathways
- Signalisation RTK
Antigène
-