Caldesmon anticorps (C-Term)

N° du produit ABIN6942328

L’anticorps anti-Caldesmon Monoclonal Lapin est utilisé pour la détection de Caldesmon dans des échantillons de Humain. Il a été validé pour WB, IHC, FACS, IHC (p) et IF (cc).

Aperçu rapide pour Caldesmon anticorps (C-Term) (ABIN6942328)

Antigène: Caldesmon (CALD1) (Caldesmon 1 (CALD1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Caldesmon est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Clone: 14G2

Détail du produit anti-Caldesmon anticorps

Épitope: C-Term

Fonction: Caldesmon (14G2) Monoclonal Antibody

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: C-terminus human Caldesmon

Isotype: IgG

Information d'application

Indications d'application: WB(1:300-5000), FCM(1:200-400), IHC-P(1:100-500), IF(ICC)(1:50-200), IHC(1 μg/Test)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur Caldesmon

Antigène: Caldesmon (CALD1) (Caldesmon 1 (CALD1))

Autre désignation: Caldesmon

Sujet:

Synonyms: Caldesmon, CDM, CALD1, CAD, CDM

Background: Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also play an essential role during cellular mitosis and receptor capping. Involved in Schwann cell migration during peripheral nerve regeneration (By similarity).

ID gène: 800

UniProt: Q05682

Pathways: Myometrial Relaxation and Contraction