Caspase 1 anticorps

N° du produit ABIN6942348

Cet anticorps Lapin Monoclonal détecte spécifiquement Caspase 1 dans WB, IHC (p), FACS et IF (cc). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour Caspase 1 anticorps (ABIN6942348)

Antigène: Caspase 1 (CASP1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Caspase 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))

Clone: 1E8

Détail du produit anti-Caspase 1 anticorps

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: C terminal Human Caspase-1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur Caspase 1

Antigène: Caspase 1 (CASP1)

Autre désignation: Caspase 1

Sujet:

Synonyms: Caspase-1, Interleukin-1 beta convertase, Interleukin-1 beta-converting enzyme, p45, CASP-1, IL-1BC, ICE, IL-1 beta-converting enzyme, CASP1

Background: Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.

ID gène: 834

UniProt: P29466

Pathways: Apoptose, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome