Recombinant CD86 anticorps (AA 1-200)

N° du produit ABIN6942458

Cet anticorps anti-CD86 Monoclonal Lapin (ABIN6942458) détecte spécifiquement CD86 dans FACS, WB et IF (cc). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant CD86 anticorps (AA 1-200) (ABIN6942458)

Antigène: CD86

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CD86 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))

Détail du produit anti-CD86 anticorps

Épitope: AA 1-200

Fonction: CD86 Recombinant Antibody

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: Recombinant human CD86 between 1 to 200 amino acids

Isotype: IgG

Information d'application

Indications d'application: WB(WB(1:500-2000)), FCM(FCM(1:50-100)), IF(ICC)(IF(ICC)(1:100-500))

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur CD86

Antigène: CD86

Autre désignation: CD86

Sujet:

Synonyms: T-lymphocyte activation antigen CD86, Activation B7-2 antigen, B70, BU63, CTLA-4 counter-receptor B7.2, FUN-1, CD_antigen: CD86, CD86, CD28LG2

Background: Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.

ID gène: 942

UniProt: P42081

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation