Frataxin anticorps

N° du produit ABIN6943478

Cet anticorps anti-Frataxin est un anticorps Lapin Monoclonal détectant Frataxin dans WB. Adapté pour Humain.

Aperçu rapide pour Frataxin anticorps (ABIN6943478)

Antigène: Frataxin (FXN)

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Frataxin est non-conjugé

Application: Western Blotting (WB)

Clone: 2G1

Détail du produit anti-Frataxin anticorps

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: Full length recombinant human Frataxin protein

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur Frataxin

Antigène: Frataxin (FXN)

Autre désignation: FRATAXIN

Sujet:

Synonyms: Frataxin, mitochondrial, FXN, Friedreich ataxia protein, FRDA, X25

Background: Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+, the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization, however, the physiological relevance is unsure as reports are conflicting and the function has only been shown using heterologous overexpression systems. Modulates the RNA-binding activity of ACO1.

ID gène: 2395

UniProt: Q16595

Pathways: Transition Metal Ion Homeostasis, Regulation of Cell Size