FURIN anticorps

N° du produit ABIN6943482

Cet anticorps Lapin Monoclonal détecte spécifiquement FURIN dans WB et IHC (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour FURIN anticorps (ABIN6943482)

Antigène: FURIN (Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp FURIN est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 8C3

Détail du produit anti-FURIN anticorps

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: Recombinant protein within human Furin aa 200-400.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000
IHC-P 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur FURIN

Antigène: FURIN (Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN))

Autre désignation: Furin

Sujet:

Synonyms: Dibasic-processing enzyme, Paired basic amino acid residue-cleaving enzyme, PACE, FURIN, FUR, PACE, PCSK3

Background: Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif. Mediates processing of TGFB1, an essential step in TGF-beta-1 activation. Probably cleaves and activates anthrax and diphtheria toxins. Required for H7N1 and H5N1 influenza virus infection probably by cleaving hemagglutinin.

ID gène: 5045

UniProt: P09958

Pathways: Signalisation Notch, Neurotrophin Signaling Pathway