ISL1 anticorps (C-Term)

N° du produit ABIN6943825

L’anticorps anti-ISL1 Monoclonal Lapin est utilisé pour la détection de ISL1 dans des échantillons de Humain. Il a été validé pour WB et IF (cc).

Aperçu rapide pour ISL1 anticorps (C-Term) (ABIN6943825)

Antigène: ISL1 (ISL LIM Homeobox 1 (ISL1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp ISL1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))

Clone: 20G6

Détail du produit anti-ISL1 anticorps

Épitope: C-Term

Fonction: Islet 1 (20G6) Monoclonal Antibody

Réactivité croisée: Humain, Souris

Purification: Purified by Protein A.

Immunogène: Recombinant Human Islet 1 between 250 amino acids to C-terminus

Isotype: IgG

Information d'application

Indications d'application: WB(1:300-5000), IF(ICC)(1:50-200)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur ISL1

Antigène: ISL1 (ISL LIM Homeobox 1 (ISL1))

Autre désignation: Islet 1

Sujet:

Synonyms: Insulin gene enhancer protein ISL-1, Islet-1, ISL1

Background: This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. [provided by RefSeq, Jul 2008]

ID gène: 3670

UniProt: P61371

Pathways: Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding