Nicastrin anticorps (AA 650-750)
Aperçu rapide pour Nicastrin anticorps (AA 650-750) (ABIN6944227)
Antigène
Voir toutes Nicastrin (NCSTN) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 650-750
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Fonction
- Nicastrin (3F10) Monoclonal Antibody
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Réactivité croisée
- Humain
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Purification
- Purified by Protein A.
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Immunogène
- Synthetic peptide within Human Nicastrin aa 650-750 (C terminal).
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Isotype
- IgG
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Indications d'application
- WB(1:300-5000)
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Date de péremption
- 12 months
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- Nicastrin (NCSTN)
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Autre désignation
- NCSTN
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Sujet
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Synonyms: Nicastrin, NCSTN, KIAA0253, ATAG1874
Background: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.
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ID gène
- 23385
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UniProt
- Q92542
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Pathways
- Signalisation Notch, Neurotrophin Signaling Pathway
Antigène
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