Nicastrin anticorps
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- Antigène Voir toutes Nicastrin (NCSTN) Anticorps
- Nicastrin (NCSTN)
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Nicastrin est non-conjugé
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Application
- Western Blotting (WB)
- Réactivité croisée
- Humain
- Purification
- Purified by Protein A.
- Immunogène
- Synthetic peptide within Human Nicastrin aa 650-750 (C terminal).
- Clone
- 3F10
- Isotype
- IgG
- Top Product
- Discover our top product NCSTN Anticorps primaire
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- Indications d'application
- WB 1:300-5000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- Nicastrin (NCSTN)
- Autre désignation
- NCSTN (NCSTN Produits)
- Synonymes
- anticorps CG7012, anticorps Dmel\\CG7012, anticorps Nct, anticorps Nic, anticorps S5A, anticorps ST96B, anticorps agro, anticorps dNct, anticorps nic, anticorps NCSTN, anticorps DKFZp469O2418, anticorps APH2, anticorps 9430068N19Rik, anticorps AA727311, anticorps Aph2, anticorps D1Dau13e, anticorps Kiaa0253, anticorps mKIAA0253, anticorps nicastrin, anticorps Nicastrin, anticorps NCSTN, anticorps nct, anticorps ncstn, anticorps CpipJ_CPIJ001617, anticorps Ncstn, anticorps aph-2
- Sujet
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Synonyms: Nicastrin, NCSTN, KIAA0253, ATAG1874
Background: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.
- ID gène
- 23385
- UniProt
- Q92542
- Pathways
- Signalisation Notch, Neurotrophin Signaling Pathway
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