PVRL2 anticorps (AA 50-250)

N° du produit ABIN6944236

L’anticorps anti-PVRL2 Monoclonal Lapin est utilisé pour la détection de PVRL2 dans des échantillons de Humain. Il a été validé pour WB, FACS, IF (p), IF (cc) et IHC (p).

Aperçu rapide pour PVRL2 anticorps (AA 50-250) (ABIN6944236)

Antigène: PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp PVRL2 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 3G7

Détail du produit anti-PVRL2 anticorps

Épitope: AA 50-250

Fonction: Nectin 2 (3G7) Monoclonal Antibody

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: Recombinant protein within human Nectin 2 aa 50-250.

Isotype: IgG

Information d'application

Indications d'application: WB(1:500-2000), FCM(1:100-500), IHC-P(1:400-800), IF(IHC-P)(1:100-500), IF(ICC)(1:50-200)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur PVRL2

Antigène: PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))

Autre désignation: NECTIN2

Sujet:

Synonyms: Nectin-2, Herpes virus entry mediator B, Nectin cell adhesion molecule 2, Poliovirus receptor-related protein 2, CD112, Herpesvirus entry mediator B, HveB, NECTIN2, HVEB, PRR2, PVRL2

Background: Nectin 2 is a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Can form trans-heterodimers with PVRL3/nectin-3.

ID gène: 5819

UniProt: Q92692

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization