PVRL2 anticorps (AA 58-212)

N° du produit ABIN5611344

Détail du produit anti-PVRL2 anticorps

Antigène: PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))

Épitope: AA 58-212

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PVRL2 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Neutralization (Neut)

Purification: purified

Immunogène: Purified recombinant fragment of human CD112 (AA: extra 58-212) expressed in E. coli.

Clone: 4A11B12

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Détails sur PVRL2

Antigène: PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))

Autre désignation: CD112 (PVRL2 Produits)

Synonymes: anticorps prr2, anticorps AI325026, anticorps AI987993, anticorps Cd112, anticorps MPH, anticorps Pvr, anticorps Pvs, anticorps nectin-2, anticorps CD112, anticorps HVEB, anticorps PRR2, anticorps PVRR2, anticorps nectin cell adhesion molecule 2, anticorps Nectin2, anticorps NECTIN2

Sujet:

Description: This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Aliases: NECTIN2, HVEB, PRR2, PVRL2, PVRR2

Poids moléculaire: 57.7 kDa

ID gène: 5819

HGNC: 5819

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization