PUMA anticorps (C-Term)
Aperçu rapide pour PUMA anticorps (C-Term) (ABIN6944729)
Antigène
Voir toutes PUMA (BBC3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- C-Term
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Fonction
- PUMA (2G6) Monoclonal Antibody
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Réactivité croisée
- Humain, Souris, Rat
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Purification
- Purified by Protein A.
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Immunogène
- Human PUMA from 150 amino acids to the C-terminus
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Isotype
- IgG
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Indications d'application
- WB(1:300-5000), FCM(1:50-200), IHC-P(1:200-400), IF(ICC)(1:50-200), IHC()
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C for 12 months.
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Date de péremption
- 12 months
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- PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
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Autre désignation
- PUMA
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Sujet
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Synonyms: Bcl-2-binding component 3, JFY-1, p53 up-regulated modulator of apoptosis, BBC3
Background: Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis (PubMed:11463391). Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis (PubMed:23340338).
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ID gène
- 27113
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UniProt
- Q9BXH1
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Pathways
- Signalisation p53, Positive Regulation of Endopeptidase Activity
Antigène
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