SOX2 anticorps (AA 221-317) (Cy5)
Aperçu rapide pour SOX2 anticorps (AA 221-317) (Cy5) (ABIN6945002)
Antigène
Voir toutes SOX2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 221-317
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Fonction
- SOX2 Polyclonal Antibody, Cy5 Conjugated
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Réactivité croisée
- Souris, Rat
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Homologie
- Human,Dog,Cow,Sheep,Horse,Chicken
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human SOX2
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Isotype
- IgG
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Indications d'application
- WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Date de péremption
- 12 months
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- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
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Autre désignation
- SOX2
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Sujet
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Synonyms: Transcription factor SOX-2, SOX2,
Background: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).
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ID gène
- 6657
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UniProt
- P48431
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Pathways
- Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
Antigène
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