TFAM anticorps

N° du produit ABIN6945143

Cet anticorps anti-TFAM est un anticorps Lapin Monoclonal détectant TFAM dans WB, IHC (p), IF (cc) et IF (p). Adapté pour Humain.

Aperçu rapide pour TFAM anticorps (ABIN6945143)

Antigène: TFAM (Transcription Factor A, Mitochondrial (TFAM))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp TFAM est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Clone: 16A1

Détail du produit anti-TFAM anticorps

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: Synthetic peptide within human mtTFA aa 50-150

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 12 months

Détails sur TFAM

Antigène: TFAM (Transcription Factor A, Mitochondrial (TFAM))

Autre désignation: TFAM

Sujet:

Synonyms: Transcription factor A, mitochondrial, Mitochondrial transcription factor 1, Transcription factor 6, Transcription factor 6-like 2, mtTFA, MtTF1, TCF-6, TFAM, TCF6, TCF6L2.

Background: Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA.

ID gène: 7019

UniProt: Q00059

Pathways: Chromatin Binding