Growth Hormone 1 anticorps
Aperçu rapide pour Growth Hormone 1 anticorps (ABIN6950857)
Antigène
Voir toutes Growth Hormone 1 (GH1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- GH/ hPL mouse mAb
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Specificité
- The antibody can recognize human Placental lactogen, and has cross-reactiin with GH protein.
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Purification
- The antibody was purified by affinity chromatography using a specific immunogen.
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Immunogène
- A synthetic peptide corresponding to the amino acid region 150 - 217 of the human GH/ hPL protein.
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Isotype
- IgG
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Indications d'application
- IHC, 1:200-1:400
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid freeze / thaw cycles
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Stock
- -20 °C
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Stockage commentaire
- Store at-20°C. Avoid freeze / thaw cycles.
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- Growth Hormone 1 (GH1)
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Autre désignation
- Growth Hormone (GH)
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Sujet
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Synonyms: Lactogen, Placental lactogen, PL, hPL, gH, GH-N, GH1, GHB5, GHN, Growth hormone 1, Growth hormone, Growth hormone B5, Growth hormone, normal, Growth hormone, pituitary, HG1, hGH-N, IGHD1B, Pituitary growth hormone, RNGHGP, SOMA_HUMAN, Somatotropin
Background: Human placental prolactin (HPL) is a 22 kD polypeptide hormone synthesized and secreted by placental syncytiotrophoblast cells, has partial homology with growth hormone. It is expressed in normal placenta, choriocarcinoma, testicular cancer. Anti-HPL antibody is commonly used in the study of trophoblastic tumors. Growth hormone (GH) is a hormone synthesized and secreted by growth hormone cells in the anterior pituitary, which can promote protein synthesis and bone development. The mechanism of stimulating body growth is to stimulate the secretion of IGF-1 by liver and other tissues. It is mainly used for the functional classification of pituitary tumor and the differentiation of primary pituitary tumor and metastatic cancer.
Gene Name: CSH1 CSH2 GH1
Protein Name: GH/ hPL
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UniProt
- P01241
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Pathways
- Signalisation NF-kappaB, Signalistation JAK/STAT, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process
Antigène
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