Cadherin-16 anticorps
Aperçu rapide pour Cadherin-16 anticorps (ABIN6950867)
Antigène
Voir toutes Cadherin-16 (CDH16) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- KSP-Cadherin mouse mAb
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Specificité
- The antibody can specifically recognize human KSP-Cadherin protein.
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Purification
- The antibody was purified by affinity chromatography using a specific immunogen.
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Immunogène
- A synthetic peptide corresponding to the amino acid region 1 - 100 of the human KSP - Cadherin protein.
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Isotype
- IgG
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Indications d'application
- IHC, 1:200-1:400
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid freeze / thaw cycles
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Stock
- -20 °C
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Stockage commentaire
- Store at-20°C. Avoid freeze / thaw cycles.
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- Cadherin-16 (CDH16)
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Autre désignation
- KSP-Cadherin
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Sujet
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Synonyms: Cadherin-16 (Kidney-specific cadherin, Ksp-cadherin)
Background: KSP-cadherin, also known as cadherin-16, is a new member of the calcium adhesion molecule family and plays an important role during embryonic development. It was specifically expressed in kidney, only in renal tubular epithelium, basement membrane and collecting duct epithelium, but not in glomerulus, renal interstitial cells and blood vessels. The loss of these adhesion molecules in renal cell tumors may be related to tumor dedifferentiation and lymph node metastasis. KSP-cadherin has a sensitivity of up to 100 % in renal chromophobe cell carcinoma and 95 % in renal eosinophilic adenoma.
Gene Name: CDH16 UNQ695/PRO1340
Protein Name: KSP-Cadherin
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ID gène
- 1014
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UniProt
- O75309
Antigène
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