KDM4A anticorps (C-Term)

N° du produit ABIN6952408

Cet anticorps anti-KDM4A Polyclonal Lapin (ABIN6952408) détecte spécifiquement KDM4A dans WB, IP, ChIP et ChIP-seq. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour KDM4A anticorps (C-Term) (ABIN6952408)

Antigène: KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KDM4A est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)

Classe de qualité: ChIP-seq Grade

Détail du produit anti-KDM4A anticorps

Épitope: C-Term

Specificité: Polyclonal antibody raised in rabbit against human JMJD2a (Jumonji domain containing 2a), using a synthetic peptide containing a sequence from the C-terminal part of the protein.

Réactivité croisée: Souris

Purification: Affinity purified

Immunogène: synthetic peptide

Information d'application

Indications d'application: ChIP 5 μg:ChIP
WB 1:500
IP 3 μg:IP

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 μg/μL

Buffer: TBS, 0,1 % BSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur KDM4A

Antigène: KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))

Autre désignation: JMJD2a

Sujet: JMJD2a (UniProtKB/Swiss-Prot entry O75164), belongs to the JMJD2 family of histone demethylases which play an important role in the establishment of the histone code. JMJD2a specifically demethylates the trimethylated K9 and K36 of histone H3, thereby converting these lysines to the dimethylated form. It has no activity towards H3K4, H3K27 and H4K20, or to the mono- and dimethylated H3K9 and H3K36. JMJD2a plays a role in the transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively.

UniProt: O75164

Pathways: L'effet Warburg