CD80 anticorps

N° du produit ABIN6961450

Cet anticorps anti-CD80 est un anticorps Hamster arménien Monoclonal détectant CD80 dans FACS, IP, IF, IHC (fro) et Func. Adapté pour Souris.

Aperçu rapide pour CD80 anticorps (ABIN6961450)

Antigène: CD80

Reactivité: Souris

Hôte: Hamster arménien

Clonalité: Monoclonal

Conjugué: Cet anticorp CD80 est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Clone: 16-10A1

Détail du produit anti-CD80 anticorps

Purification: This monoclonal antibody preparation was purified from tissue culture supernatant via affinity chromatography. For In Vivo Ready™ (IVR) products, each preparation is also evaluated for endotoxin levels using the LAL assay. It is recommended to store the product undiluted at 4°C. Do not freeze.

niveau d'endotoxine: Low endotoxin: < 0.01 EU/ug

Isotype: IgG

Information d'application

Indications d'application: This purified format is guaranteed to be >90 % pure as determined by SDS-PAGE analysis.

Commentaires:

2.0 mg/mL

Restrictions: For Research Use only

Stockage

Buffer: 10 mM NaH2PO4, 150 mM NaCl, pH 7.2

Agent conservateur: Azide free

Stock: 4 °C

Stockage commentaire: 2-8°C

Date de péremption: 12 months

Détails sur CD80

Antigène: CD80

Autre désignation: CD80 (B7-1)

Sujet: The 16-10A1 antibody reacts with mouse CD80, also known as B7-1, a 55 kDa type I transmembrane protein ligand for CD152 (CTLA-4) and for CD28, a co- stimulatory receptor for the T cell receptor (TCR). CD28 also binds a second B7 ligand known as CD86 (B7-2). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 or CTLA-4 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response.

ID gène: 12519

UniProt: Q00609

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints