CD80 anticorps
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- Antigène Voir toutes CD80 Anticorps
- CD80
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Reactivité
- Souris
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Hôte
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Hamster arménien
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD80 est non-conjugé
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Application
- Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
- Purification
- This monoclonal antibody preparation was purified from tissue culture supernatant via affinity chromatography. For In Vivo Ready™ (IVR) products, each preparation is also evaluated for endotoxin levels using the LAL assay. It is recommended to store the product undiluted at 4°C. Do not freeze.
- niveau d'endotoxine
- Low endotoxin: < 0.01 EU/ug
- Clone
- 16-10A1
- Isotype
- IgG
- Top Product
- Discover our top product CD80 Anticorps primaire
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anti-CD80 (CD80) (AA 35-288) antibody
CD80 Reactivité: Humain FACS, WB, ELISA, IHC, ICC, Neut Hôte: Souris Monoclonal 1G3D7 unconjugated
anti-CD80 (CD80) antibodyCD80 Reactivité: Souris, Chien FACS, IP, IHC (fro) Hôte: Hamster arménien Monoclonal 16-10A1 unconjugated
anti-CD80 (CD80) (AA 38-246) antibodyCD80 Reactivité: Souris WB, IP, IHC, ICC Hôte: Lapin Polyclonal unconjugated
anti-CD80 (CD80) (Extracellular Domain) antibodyCD80 Reactivité: Humain FACS, IP Hôte: Souris Monoclonal MEM-233 unconjugated
anti-CD80 (CD80) (Extracellular Domain) antibody (FITC)CD80 Reactivité: Humain FACS Hôte: Souris Monoclonal MEM-233 FITC
anti-CD80 (CD80) (AA 251-321) antibodyCD80 Reactivité: Humain, Souris, Rat WB, ELISA, IHC (p), ICC, IHC (fro), IF (cc), IF (p) Hôte: Lapin Polyclonal unconjugated
anti-CD80 (CD80) (Extracellular Domain) antibody (PE)CD80 Reactivité: Humain FACS Hôte: Souris Monoclonal MEM-233 PE
anti-CD80 (CD80) (Extracellular Domain) antibody (APC)CD80 Reactivité: Humain FACS Hôte: Souris Monoclonal MEM-233 APC
anti-CD80 (CD80) (Extracellular Domain) antibody (PerCP)CD80 Reactivité: Humain FACS Hôte: Souris Monoclonal MEM-233 PerCP
anti-CD80 (CD80) antibodyCD80 Reactivité: Humain ELISA, IHC, ICC Hôte: Souris Monoclonal 2A2 unconjugated
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- Indications d'application
- This purified format is guaranteed to be >90 % pure as determined by SDS-PAGE analysis.
- Commentaires
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2.0 mg/mL
- Restrictions
- For Research Use only
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- Buffer
- 10 mM NaH2PO4, 150 mM NaCl, pH 7.2
- Agent conservateur
- Azide free
- Stock
- 4 °C
- Stockage commentaire
- 2-8°C
- Date de péremption
- 12 months
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- Antigène
- CD80
- Autre désignation
- CD80 (B7-1) (CD80 Produits)
- Synonymes
- anticorps B7, anticorps B7-1, anticorps B7.1, anticorps BB1, anticorps CD28LG, anticorps CD28LG1, anticorps LAB7, anticorps B71, anticorps Cd28l, anticorps Ly-53, anticorps Ly53, anticorps MIC17, anticorps TSA1, anticorps CD80 molecule, anticorps Cd80 molecule, anticorps CD80 antigen, anticorps CD80, anticorps Cd80
- Sujet
- The 16-10A1 antibody reacts with mouse CD80, also known as B7-1, a 55 kDa type I transmembrane protein ligand for CD152 (CTLA-4) and for CD28, a co- stimulatory receptor for the T cell receptor (TCR). CD28 also binds a second B7 ligand known as CD86 (B7-2). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 or CTLA-4 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response.
- ID gène
- 12519
- UniProt
- Q00609
- Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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