GM-CSF anticorps

N° du produit ABIN6963888

L’anticorps Rat Monoclonal anti-GM-CSF a été validé pour ELISA et ELISpot. Il convient pour détecter GM-CSF dans des échantillons de Humain et Non-Human Primate. Il y a 5+ publications disponibles.

Aperçu rapide pour GM-CSF anticorps (ABIN6963888)

Antigène: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Reactivité: Humain, Non-Human Primate

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp GM-CSF est non-conjugé

Application: ELISA, ELISpot

Clone: 21C11

Détail du produit anti-GM-CSF anticorps

Specificité: Native and recombinant GM-CSF

Réactivité croisée (Details): The monoclonal antibody cross-reacts with GM-CSF from non-human primates.

Attributs du produit: This monoclonal antibody enables specific detection of human GM-CSF in immunoassays such as ELISpot, FluoroSpot, and ELISA. Serum/Plasma samples

Purification: Purified from in vitro cultures by protein G affinity chromatography.

Stérilité: 0.2 μm filtered

Immunogène: Recombinant human GM-CSF

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

ABIN6963888 and ABIN7489151 is recommended as capture mAb in ELISpot, FluoroSpot, and ELISA in combination with detection mAb ABIN6963889, ABIN7489152 and ABIN6964026 .

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: supplied at 1 mg/mL in PBS with 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Date de péremption: 18 months

Références pour anticorps anti-GM-CSF (ABIN6963888)

Jarrett, Salio, Lloyd-Lavery, Subramaniam, Bourgeois, Archer, Cheung, Hardman, Chandler, Salimi, Gutowska-Owsiak, de la Serna, Fallon, Jolin, Mckenzie, Dziembowski, Podobas, Bal, Johnson, Moody et al.: "Filaggrin inhibits generation of CD1a neolipid antigens by house dust mite-derived phospholipase. ..." dans: Science translational medicine, Vol. 8, Issue 325, pp. 325ra18, (2016) (PubMed).

Myers, Cooper, Kem, Stavrakis, Kosanke, Shevach, Fairweather, Stoner, Cox, Cunningham: "Cardiac myosin-Th17 responses promote heart failure in human myocarditis." dans: JCI insight, Vol. 1, Issue 9, (2016) (PubMed).

Morita, Yamamoto, Suzuki, Mori, Igarashi, Sugita: "Molecular requirements for T cell recognition of N-myristoylated peptides derived from the simian immunodeficiency virus Nef protein." dans: Journal of virology, Vol. 87, Issue 1, pp. 482-8, (2013) (PubMed).

Gille-Johnson, Smedman, Gudmundsdotter, Somell, Nihlmark, Paulie, Andersson, Gårdlund: "Circulating monocytes are not the major source of plasma cytokines in patients with sepsis." dans: Shock (Augusta, Ga.), Vol. 38, Issue 6, pp. 577-83, (2013) (PubMed).

Mäkitalo, Andersson, Areström, Karlén, Villinger, Ansari, Paulie, Thorstensson, Ahlborg: "ELISpot and ELISA analysis of spontaneous, mitogen-induced and antigen-specific cytokine production in cynomolgus and rhesus macaques." dans: Journal of immunological methods, Vol. 270, Issue 1, pp. 85-97, (2002) (PubMed).

Détails sur GM-CSF

Antigène: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Autre désignation: GMCSF

ID gène: 1437

Pathways: Signalistation JAK/STAT, Cellular Response to Molecule of Bacterial Origin