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APOB anticorps
APOB
Reactivité: Humain, Non-Human Primate
WB, ELISA
Hôte: Souris
Monoclonal
LDL 20-17
unconjugated
N° du produit ABIN6963944
Détail du produit anti-APOB anticorps
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Antigène
Voir toutes APOB Anticorps
APOB
(Apolipoprotein B (APOB))
Reactivité
Toutes les réactivités sur APOB Anticorps
Humain, Non-Human Primate
Hôte
Toutes les hôtes sur APOB Anticorps
Souris
Clonalité
Toutes les clonalités sur APOB Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers APOB Anticorps
Cet anticorp APOB est non-conjugé
Application
Tous les applications à travers APOB Anticorps.
Western Blotting (WB), ELISA
Specificité
Native apoB in the form of LDL.
Réactivité croisée (Details)
The monoclonal antibody cross-reacts with apoB from non-human primates.
Purification
Purified from in vitro cultures by protein G affinity chromatography.
Immunogène
Human LDL
Clone
LDL 20-17
Isotype
IgG2a
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Alternatives
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Information d'application
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Indications d'application
For quantification of apoB in serum/plasma samples and cell culture supernatants using ELISA. LDL 20/17 is recommended as coating mAb in combination with detection mAb LDL 11 . The antibodies are also suitable for immunoprecipitation and Western blot.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
1 mg/mL
Buffer
supplied at 1 mg/mL in PBS with 0.02 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.
Date de péremption
18 months
Références pour anticorps anti-APOB (ABIN6963944)
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Yu, Rimbert, Palmer, Toyohara, Xia, Xia, Ferreira, Chen, Chen, Loaiza, Horwitz, Kacergis, Zhao, Soukas, Kuivenhoven, Kathiresan, Cowan : "GPR146 Deficiency Protects against Hypercholesterolemia and Atherosclerosis. " dans: Cell , Vol. 179 , Issue 6 , pp. 1276-1288.e14 , (2020 ) (PubMed ).
Cayo, Mallanna, Di Furio, Jing, Tolliver, Bures, Urick, Noto, Pashos, Greseth, Czarnecki, Traktman, Yang, Morrisey, Grompe, Rader, Duncan : "A Drug Screen using Human iPSC-Derived Hepatocyte-like Cells Reveals Cardiac Glycosides as a Potential Treatment for Hypercholesterolemia. " dans: Cell stem cell , Vol. 20 , Issue 4 , pp. 478-489.e5 , (2017 ) (PubMed ).
Vu, Bemis, Benson, Bista, Carney, Fahrner, Lee, Liu, Lonkar, Milne, Nichols, Picarella, Shoelson, Smith, Ting, Wensley, Yeager, Zimmer, Jirousek : "Synthesis and Characterization of Fatty Acid Conjugates of Niacin and Salicylic Acid. " dans: Journal of medicinal chemistry , Vol. 59 , Issue 3 , pp. 1217-31 , (2016 ) (PubMed ).
Bissig-Choisat, Wang, Legras, Saha, Chen, Bell, Pankowicz, Hill, Barzi, Leyton, Leung, Kruse, Himes, Goss, Wilson, Chan, Lagor, Bissig : "Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model. " dans: Nature communications , Vol. 6 , pp. 7339 , (2015 ) (PubMed ).
Derwall, Malhotra, Lai, Beppu, Aikawa, Seehra, Zapol, Bloch, Yu : "Inhibition of bone morphogenetic protein signaling reduces vascular calcification and atherosclerosis. " dans: Arteriosclerosis, thrombosis, and vascular biology , Vol. 32 , Issue 3 , pp. 613-22 , (2012 ) (PubMed ).
Détails sur APOB
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Antigène
APOB
(Apolipoprotein B (APOB))
Autre désignation
apoB (APOB Produits )
Synonymes
anticorps FLDB, anticorps LDLCQ4, anticorps Ac1-060, anticorps Apo B-100, anticorps ApoB-100, anticorps ApoB-48, anticorps AI315052, anticorps apob-100, anticorps apob-48, anticorps APOB-100, anticorps ApoB(100), anticorps APOB, anticorps apolipoprotein B, anticorps APOB, anticorps Apob
ID gène
338
Pathways
Lipid Metabolism
Vus récemment
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