POLR2B anticorps (N-Term)

N° du produit ABIN6972544

Détail du produit anti-POLR2B anticorps

Antigène: POLR2B (Polymerase (RNA) II (DNA Directed) Polypeptide B, 140kDa (POLR2B))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POLR2B est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Attributs du produit: POLR2B (polymerase (RNA) II (DNA directed) polypeptide B, 140 kDa) DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB2 is part of the core element with the central large cleft, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template (By similarity). POLR2B antibody (pAb) was raised in a Rabbit host. It has been validated for use in Immunoprecipitation and Western blot, it has been shown to react with Human samples.

Purification: Affinity Purified

Immunogène: This antibody was raised against a peptide within the N-terminal region of human POLR2B.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Détails sur POLR2B

Antigène: POLR2B (Polymerase (RNA) II (DNA Directed) Polypeptide B, 140kDa (POLR2B))

Autre désignation: POLR2B (POLR2B Produits)

Synonymes: anticorps Pol2rb, anticorps Rpb140, anticorps Rpb2, anticorps POL2RB, anticorps RPB2, anticorps hRPB140, anticorps hsRPB2, anticorps RNA polymerase II subunit B, anticorps polymerase (RNA) II (DNA directed) polypeptide B, 140kDa, anticorps DNA-directed RNA polymerase II subunit RPB2, anticorps polymerase (RNA) II (DNA directed) polypeptide B, anticorps polymerase (RNA) II (DNA directed) polypeptide B, 140kDa L homeolog, anticorps POLR2B, anticorps polr2b, anticorps LOC100640211, anticorps Polr2b, anticorps polr2b.L, anticorps rpb-2

Poids moléculaire: 135 kDa

NCBI Accession: NP_000929

Pathways: Regulatory RNA Pathways, Réparation de l'ADN