TDG anticorps

N° du produit ABIN6972851

Cet anticorps Lapin Polyclonal détecte spécifiquement TDG dans WB. Il présente une réactivité envers Souris.

Aperçu rapide pour TDG anticorps (ABIN6972851)

Antigène: TDG (Thymine-DNA Glycosylase (TDG))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TDG est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TDG anticorps

Attributs du produit: In the DNA of higher eukaryotes, hydrolytic deamination of 5-methylcytosine to thymine leads to the formation of G/T mismatches. In addition, TET proteins oxidize 5- methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), 5- formylcytosine (5fC), and 5-carboxylcytosine (5caC). TDG / Thymine-DNA glycosylase functions to correct G/T mispairs to G/C pairs and plays a role in active DNA demethylation by recognizing 5fC and 5caC and converting these to cystosine through the base excision repair (BER) pathway. TDG / Thymine-DNA glycosylase antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Mouse samples.

Purification: Protein A Chromatography

Immunogène: This antibody was raised against a full-length recombinant protein corresponding to mouse thymine DNA glycosylase (TDG).

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Détails sur TDG

Antigène: TDG (Thymine-DNA Glycosylase (TDG))

Autre désignation: TDG / Thymine-DNA glycosylase

Poids moléculaire: 55 kDa

NCBI Accession: NP_766140

Pathways: Réparation de l'ADN, Chromatin Binding