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Caspase 1 (p10) anticorps (AA 321-404) (Biotin)

CASP-1 (p10) Reactivité: Humain, Souris WB, ELISA Hôte: Lapin Polyclonal Biotin
N° du produit ABIN6982755
  • Antigène Tous les produits Caspase 1 (p10) (CASP-1 (p10))
    Caspase 1 (p10) (CASP-1 (p10))
    Épitope
    • 16
    • 15
    • 15
    • 1
    AA 321-404
    Reactivité
    • 47
    • 34
    • 32
    • 16
    Humain, Souris
    Hôte
    • 47
    • 2
    Lapin
    Clonalité
    • 47
    • 2
    Polyclonal
    Conjugué
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    Cet anticorp Caspase 1 (p10) est conjugé à/à la Biotin
    Application
    • 49
    • 28
    • 26
    • 26
    • 8
    • 6
    • 6
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
     Réactivité croisée
    Humain, Souris
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Caspase-1 P10
    Isotype
    IgG
  • Indications d'application
    WB 1:300-5000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    Caspase 1 (p10) (CASP-1 (p10))
    Autre désignation
    Caspase-1 P10 (CASP-1 (p10) Produits)
    Sujet

    Synonyms: caspase-1 isoform alpha p10 subunit, CASP 1, CASP1, Caspase 1 apoptosis related cysteine peptidase, Caspase 1 apoptosis related cysteine protease, Caspase1, ICE, IL 1 beta converting enzyme, IL 1BC, IL1B convertase, IL1BC, IL1BCE, Interleukin 1 beta convertase, Interleukin 1 beta convertase precursor, Interleukin 1 beta converting enzyme. CASP-1, Interleukin-1 beta convertase, IL-1BC, Interleukin-1 beta-converting enzyme, ICE, IL-1 beta-converting enzyme, p45, Caspase-1 subunit p10.,

    Background: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing of this gene results in five transcript variants encoding distinct isoforms. [provided by RefSeq].

    ID gène
    834
    UniProt
    P29466
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