ADAP2 anticorps (AA 201-300) (Cy3)

N° du produit ABIN6983290

Cet anticorps Lapin Polyclonal détecte spécifiquement ADAP2 dans WB, IF (cc) et IF (p). Il présente une réactivité envers Humain et Rat.

Aperçu rapide pour ADAP2 anticorps (AA 201-300) (Cy3) (ABIN6983290)

Antigène: ADAP2 (ArfGAP with Dual PH Domains 2 (ADAP2))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADAP2 est conjugé à/à la Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-ADAP2 anticorps (Cy3)

Épitope: AA 201-300

Specificité: Possible cross-reactivity with ADAP1 (85 % homology with the immunogen sequence, 43 kDa)

Réactivité croisée: Humain, Rat

Homologie: Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Centaurin alpha 2

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur ADAP2

Antigène: ADAP2 (ArfGAP with Dual PH Domains 2 (ADAP2))

Autre désignation: Centaurin alpha 2

Sujet:

Synonyms: ADAP2, ADAP2_HUMAN, Arf-GAP with dual PH domain-containing protein 2, ArfGAP with dual PH domains 2, cent b, Centa 2, CENTA2, Centaurin alpha 2, Centaurin alpha 2 protein, Centaurin beta, Centaurin-alpha-2, Cnt-a2, HSA272195.

Background: The ADP-ribosylation factor (ARF) family of small GTP-binding proteins are involved in vesicular transport regulation and in controlling cytoskeletal organization and cell adhesion. The Centaurin GTPase-activating protein family comprise a subset of ARF regulatory molecules that transduce PI 3-kinase activation into coordinated control of ARF-dependent pathways. This family includes ASAP1, ACAP1, ACAP2, AGAP1, ARAP1, ARAP2, Centaurin a1, Centaurin g3 and the recently discovered Centaurin a2. Expressed in a wide variety of tissues such as fat, heart and skeletal muscle, Centaurin a2 is thought to negatively regulate ARF-mediated actin rearrangement by binding activated PI 3-kinase. Although the exact function of Centaurin a2 is not yet known, its high sequence similarity with Centaurin a1 suggests that it may also act as an ARF6 GTPase.

ID gène: 55803

UniProt: Q9NPF8