DBNL anticorps (AA 201-300) (Cy3)

N° du produit ABIN6983691

Cet anticorps anti-DBNL est un anticorps Lapin Polyclonal détectant DBNL dans WB, IF (cc) et IF (p). Adapté pour Souris.

Aperçu rapide pour DBNL anticorps (AA 201-300) (Cy3) (ABIN6983691)

Antigène: DBNL (Drebrin-Like (DBNL))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DBNL est conjugé à/à la Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-DBNL anticorps (Cy3)

Épitope: AA 201-300

Réactivité croisée: Souris

Homologie: Human

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human HIP55

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur DBNL

Antigène: DBNL (Drebrin-Like (DBNL))

Autre désignation: HIP55

Sujet:

Synonyms: ABP1, Actin-binding protein 1, Cervical mucin associated protein, Cervical mucin-associated protein, Cervical SH3P7, CMAP, Dbnl, DBNL_HUMAN, Drebrin F, drebrin like, Drebrin like protein, Drebrin-F, Drebrin-like protein, HIP 55, HIP-55, HPK1 interacting protein of 55 kDa, HPK1-interacting protein of 55 kDa, SH3 domain containing protein 7, SH3 domain-containing protein 7, SH3P7, Src Homology 3 Domain Containing Protein, src homology 3 domain containing protein HIP

Background: Adapter protein that binds F-actin and DNM1, and thereby plays a role in receptor-mediated endocytosis. Plays a role in the reorganization of the actin cytoskeleton, formation of cell projections, such as neurites, in neuron morphogenesis and synapse formation via its interaction with WASL and COBL. Does not bind G-actin and promote actin polymerization by itself. Required for the formation of organized podosome rosettes (By similarity). May act as a common effector of antigen receptor-signaling pathways in leukocytes. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes.

ID gène: 28988

UniProt: Q9UJU6

Pathways: TCR Signaling, Regulation of Actin Filament Polymerization