STIM1 anticorps (AA 601-685) (Cy3)

N° du produit ABIN6983819

L’anticorps Lapin Polyclonal anti-STIM1 a été validé pour IF (p) et IF (cc). Il convient pour détecter STIM1 dans des échantillons de Humain et Rat.

Aperçu rapide pour STIM1 anticorps (AA 601-685) (Cy3) (ABIN6983819)

Antigène: STIM1 (Stromal Interaction Molecule 1 (STIM1))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STIM1 est conjugé à/à la Cy3

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Détail du produit anti-STIM1 anticorps (Cy3)

Épitope: AA 601-685

Réactivité croisée: Humain, Rat

Homologie: Mouse,Cow,Sheep,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human STIM1

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur STIM1

Antigène: STIM1 (Stromal Interaction Molecule 1 (STIM1))

Autre désignation: STIM1

Sujet:

Synonyms: GOK, SIM, STIM 1, STIM1, STIM-1, Stim1 stromal interaction molecule 1, STIM1_HUMAN, STIM1L, Stromal interaction molecule 1.

Background: Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit, TMEM142A/ORAI1.

ID gène: 6786

UniProt: Q13586

Pathways: TCR Signaling, BCR Signaling