SMAD2 anticorps (pSer250) (Cy7)

N° du produit ABIN6986540

L’anticorps Lapin Polyclonal anti-SMAD2 a été validé pour WB et FACS. Il convient pour détecter SMAD2 dans des échantillons de Humain et Souris.

Aperçu rapide pour SMAD2 anticorps (pSer250) (Cy7) (ABIN6986540)

Antigène: SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMAD2 est conjugé à/à la Cy7

Application: Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-SMAD2 anticorps (Cy7)

Épitope: pSer250

Réactivité croisée: Humain, Souris

Homologie: Rat,Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthesised phosphopeptide derived from human Smad2 around the phosphorylation site of Ser250

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur SMAD2

Antigène: SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))

Autre désignation: Smad2

Sujet:

Synonyms: Smad2 (phospho S250), p-Smad2 (phospho S250), hMAD 2, hMAD 3, hSMAD2, hSMAD3, Mad related protein 2, MADH2, MADH3, MADR2, Mothers against DPP homolog 2, Mothers against DPP homolog 3, Sma and Mad related protein 2, SMA and MAD related protein 3, SMAD 2, SMAD 3, SMAD family member 2, SMAD family member 3.

Background: Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma.

ID gène: 4087

UniProt: Q15796

Pathways: Cycle Cellulaire, Hormone Transport, Chromatin Binding, Protein targeting to Nucleus