CDK7 anticorps (pThr170) (FITC)

N° du produit ABIN6986692

Cet anticorps Lapin Polyclonal détecte spécifiquement CDK7 dans WB, IF (cc) et IF (p). Il présente une réactivité envers Humain.

Aperçu rapide pour CDK7 anticorps (pThr170) (FITC) (ABIN6986692)

Antigène: CDK7 (Cyclin-Dependent Kinase 7 (CDK7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK7 est conjugé à/à la FITC

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-CDK7 anticorps (FITC)

Épitope: pThr170

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated Synthesised phosphopeptide derived from human CDK7 around the phosphorylation site of Thr170

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur CDK7

Antigène: CDK7 (Cyclin-Dependent Kinase 7 (CDK7))

Autre désignation: CDK7

Sujet:

Synonyms: CDK7 (phospho Thr170), CDK7 (phospho T170), Cyclin H, MAT1, Cyclin Dependent Kinase 7, CAK1, MO15, CDKN7, serine/threonine kinase, STK1, serine/threonine protein kinase 1, MO15 homolog,Xenopus laevis, cdk-activating kinase, Cdk-activating kinase, serine/threonine protein kinase MO15, homolog of Xenopus MO15 Cdk-activating kinase, kinase subunit of CAK, 39 KDa protein kinase, CR4 protein kinase, CRK4, CDK7_HUMAN.

Background: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.

ID gène: 1022

UniProt: P50613

Pathways: Cycle Cellulaire, Réparation de l'ADN, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, M Phase