HDAC1 anticorps (AA 393-482)
Aperçu rapide pour HDAC1 anticorps (AA 393-482) (ABIN6989114)
Antigène
Voir toutes HDAC1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 393-482
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Specificité
- KO-Validated
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Réactivité croisée
- Humain
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Homologie
- Mouse,Rat
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Purification
- Purified by Protein A.
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 393-482 of human HDAC1 (NP_004955.2).
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IP(1-2 μg)
IF() -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C for 12 months.
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Date de péremption
- 12 months
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- HDAC1 (Histone Deacetylase 1 (HDAC1))
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Autre désignation
- HDAC1
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Sujet
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Synonyms: GON-10,HD1,RPD3,RPD3L1,HDAC1
Background: Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
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ID gène
- 3065
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UniProt
- Q13547
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Pathways
- Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Mitotic G1-G1/S Phases, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Negative Regulation of intrinsic apoptotic Signaling, Embryonic Body Morphogenesis
Antigène
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