Recombinant Cyclin E2 anticorps (C-Term)

N° du produit ABIN6989714

L’anticorps anti-Cyclin E2 Monoclonal Lapin est utilisé pour la détection de Cyclin E2 dans des échantillons de Humain. Il a été validé pour WB, FACS, IHC (p), IF (cc), IF (p) et IHC (fro).

Aperçu rapide pour Recombinant Cyclin E2 anticorps (C-Term) (ABIN6989714)

Antigène: Cyclin E2 (CCNE2)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Cyclin E2 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-Cyclin E2 anticorps

Épitope: C-Term

Fonction: Cyclin E2 Recombinant Antibody

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: Recombinant human Cyclin E2 protein, around C-terminal 100aa.

Isotype: IgG

Information d'application

Indications d'application: WB(WB(1:500-2000)), FCM(FCM(1:50-100)), IHC-P(IHC-P(1:50-200)), IHC-F(IHC-F(1:50-200)), IF(IHC-P)(IF(IHC-P)(1:50-200)), IF(ICC)(IF(ICC)(1:50-200))

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur Cyclin E2

Antigène: Cyclin E2 (CCNE2)

Autre désignation: Cyclin E2

Sujet:

Synonyms: Cyclin E2 phospho T392, p-Cyclin E2 phospho T392,CCN E2, CCNE 2, CCNE2, CCNE2 protein, CYC E2, CYCE 2, CYCE2, CyclinE2, G1/S-specic cyclin E2, G1/S-specic cyclin E2.

Background: The human Cyclin E2 gene encodes a 404 amino acid protein that is most closely related to Cyclin E. Cyclin E2 mRNA levels peaks at the G1 / S transition. Cyclin E2 associates with Cdk2 in a functional kinase complex that is inhibited by both p27 (Kip1) and p21 (Cip1). Cyclin E2 / Cdk2 phosphorylates histone H1 in vitro. G1 cyclin E controls the initiation of DNA synthesis by activating CDK2. Abnormally high levels of cyclin E expression have frequently been observed in human cancers. Unlike Cyclin E1, which is expressed in great majority of proliferating normal and neoplastically transformed cells, Cyclin E2 levels are low to undetectable in non transformed cells and increase significantly in neoplasm derived cells.

ID gène: 9134

UniProt: O96020

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases