MAP3K14 anticorps (C-Term)

N° du produit ABIN6990248

L’anticorps Lapin Polyclonal anti-MAP3K14 a été validé pour WB, ELISA, IF et ICC. Il convient pour détecter MAP3K14 dans des échantillons de Humain.

Aperçu rapide pour MAP3K14 anticorps (C-Term) (ABIN6990248)

Antigène: MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP3K14 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-MAP3K14 anticorps

Épitope: C-Term

Purification: NIK Antibody is affinity chromatography purified via peptide column.

Immunogène: NIK antibody was raised against a 17 amino acid peptide near the carboxy terminus of human NIK. The immunogen is located within the last 50 amino acids of NIK.

Isotype: IgG

Information d'application

Indications d'application: NIK antibody can be used for detection of NIK by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: NIK Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: NIK antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur MAP3K14

Antigène: MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))

Autre désignation: NIK

Sujet: NIK Antibody: Nuclear factor kappa B (NF-κ,B) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-κ,B mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFα, LPS and mitogens. A serine/threonine protein kinase which mediates NF-κ,B activation by IL-1, TNFα, and CD95 was identified recently and designated NIK (for NF-κ,B inducing kinase). NIK is an activator of Iκ,B kinase alpha and beta (IKKα, and IKKβ,). Therefore, NIK is a key molecule in the NF-κ,B signaling pathway leading to the induction of a variety of gene expression in response to proinflammatory cytokines and bacteria products.

Poids moléculaire: Predicted: 104 kDa

ID gène: 9020

UniProt: Q99558

Pathways: Signalisation NF-kappaB, TCR Signaling