CARD10 anticorps (C-Term)

N° du produit ABIN6990395

L’anticorps Lapin Polyclonal anti-CARD10 a été validé pour WB, ELISA, IF et ICC. Il convient pour détecter CARD10 dans des échantillons de Humain et Souris.

Aperçu rapide pour CARD10 anticorps (C-Term) (ABIN6990395)

Antigène: CARD10 (Caspase Recruitment Domain Family, Member 10 (CARD10))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CARD10 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-CARD10 anticorps

Épitope: C-Term

Purification: CARD10 Antibody is immunoaffinity purified .

Immunogène: CARD10 antibody was raised against a synthetic peptide corresponding to 14 amino acids at the C-terminus of human CARD10. The immunogen is located within the last 50 amino acids of CARD10.

Isotype: IgG

Information d'application

Indications d'application: CARD10 antibody can be used for detection of CARD10 by Western blot at 5 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: CARD10 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: CARD10 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur CARD10

Antigène: CARD10 (Caspase Recruitment Domain Family, Member 10 (CARD10))

Autre désignation: CARD10

Sujet: CARD10 Antibody: Apoptosis is related to many diseases and development. Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, Bcl-10, and ASC. A novel CARD-containing protein was recently identified and designated CARD10. This protein belongs to the membrane-associated guanylate kinase-like (MAGUK) family of proteins that can function as molecular scaffolds that assist assembly of signal transduction molecules. CARD 10 interacts with Bcl-10, a Bcl protein that promotes apoptosis, caspase-9 maturation and activation of NF-κ,B. CARD 10 and the related protein CARMA1 also associate with NEMO, the regulatory subunit of the Iκ,K complex, demonstrating its importance in the regulation of NF-κ,B transcription factor activation.

Poids moléculaire: Predicted: 116 kDa

Observed: 115 kDa

ID gène: 29775

UniProt: Q9BWT7

Pathways: S100 Proteins