TICAM2 anticorps (C-Term)
Aperçu rapide pour TICAM2 anticorps (C-Term) (ABIN6990461)
Antigène
Voir toutes TICAM2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Purification
- TIRP Antibody is Ion exchange chromatography purified.
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Immunogène
- TIRP antibody was raised against a peptide corresponding to amino acids near the C-terminus of human TIRP. The immunogen is located within the last 50 amino acids of TIRP.
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Isotype
- IgG
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Indications d'application
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TIRP antibody can be used for detection of TIRP by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human, mouse, and rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- TIRP Antibody is supplied in PBS containing 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,4 °C
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Stockage commentaire
- TIRP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))
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Autre désignation
- TIRP
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Sujet
- TIRP Antibody: TIRP is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TIRP, along with other molecules such as TRIF, MAL, and MyD88, serves as an adaptor protein that allows for the interaction and activation of the IL-1R-associated kinase (IRAK) family, the subsequent activation of TNF receptor associated factor (TRAF)-6, and ultimately the activation of NF-κ,B. Expression of TIRP appears to be essential for TLR4 signalling.
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ID gène
- 353376
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UniProt
- Q86XR7
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Pathways
- Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
Antigène
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