BOK anticorps (N-Term)

N° du produit ABIN6990478

Cet anticorps Lapin Polyclonal détecte spécifiquement BOK dans ELISA et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour BOK anticorps (N-Term) (ABIN6990478)

Antigène: BOK (BCL2-Related Ovarian Killer (BOK))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BOK est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-BOK anticorps

Épitope: N-Term

Specificité: At least three isoforms of BOK are known to exist, this antibody will not detect the smallest isoform. BOK antibody is predicted to not cross-react with other Bcl-2 protein family members

Purification: BOK Antibody is affinity chromatography purified via peptide column.

Immunogène: BOK antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human BOK. The immunogen is located within the first 50 amino acids of BOK.

Isotype: IgG

Information d'application

Indications d'application: BOK antibody can be used for detection of BOK by immunohistochemistry at 5 μ,g/mL.

Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: BOK Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: BOK antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur BOK

Antigène: BOK (BCL2-Related Ovarian Killer (BOK))

Autre désignation: BOK

Sujet: BOK Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. BOK, a pro-apoptotic Bcl-2 family member, was initially identified in the ovary, and was found to interact with other Bcl-2 family members such as Mcl-1 and Bfl-1. BOK expression is high during early placental development, suggesting that it may also play a role in regulating trophoblast cell proliferation.

ID gène: 666

UniProt: Q9UMX3

Pathways: Positive Regulation of Endopeptidase Activity