Caspase 6 anticorps (AA 160-210)

N° du produit ABIN6990522

Cet anticorps anti-Caspase 6 est un anticorps Lapin Polyclonal détectant Caspase 6 dans WB, ELISA, ICC et IF. Adapté pour Humain.

Aperçu rapide pour Caspase 6 anticorps (AA 160-210) (ABIN6990522)

Antigène: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caspase 6 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Détail du produit anti-Caspase 6 anticorps

Épitope: AA 160-210

Specificité: Depending on cell lines or tissues used, either full-length or other cleavage products may be observed.

Purification: Caspase-6 Antibody is immunoaffinity purified .

Immunogène: Caspase-6 antibody was raised against a 15 amino acid synthetic peptide from near the center of human Caspase-6. The immunogen is located within amino acids 160 - 210 of Caspase-6.

Isotype: IgG

Information d'application

Indications d'application: Casp-6 antibody can be used for the detection of Caspase-6 by Western blot at 1 and 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 1 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Caspase-6 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: Caspase-6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur Caspase 6

Antigène: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Autre désignation: Caspase-6

Sujet: Caspase-6 Antibody: Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. The apoptotic subfamily can be further divided into initiator caspases, which are activated in response to death signals, and executioner caspases, which are activated by the initiator caspases and are responsible for cleavage of cellular substrates that ultimately lead to cell death. Caspase-6 is an executioner caspase that was identified based on its homology with human caspases 2 and 3 as well as the C. elegans cell death protein CED-3. It possesses two isoforms, of which only the longer form possesses protease activity. Caspase-6 is highly expressed in adult brain and may play a role in several neuronal pathologies.

ID gène: 839

NCBI Accession: NP_001217

UniProt: P55212

Pathways: Apoptose, Caspase Cascade in Apoptosis