IRF7 anticorps (AA 200-230)
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- Antigène Voir toutes IRF7 Anticorps
- IRF7 (Interferon Regulatory Factor 7 (IRF7))
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Épitope
- AA 200-230
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IRF7 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- Several isoforms of IRF7 are known to exist.
- Purification
- IRF7 Antibody is affinity chromatography purified via peptide column.
- Immunogène
- Anti-IRF7 antibody was raised against a peptide corresponding to 17 amino acids near the center of human IRF7. The immunogen is located within amino acids 200-230 of IRF7.
- Isotype
- IgG
- Top Product
- Discover our top product IRF7 Anticorps primaire
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- Indications d'application
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WB: 0.5-1 μ,g/mL, IF: 20 μ,g/mL, IHC: 2-5 μ,g/mL.
Antibody validated: Western Blot in human, mouse and rat samples. Immunofluorescence in mouse samples. Immunohistochemistry in human, mouse and rat samples. All other applications and species not yet tested. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- IRF7 Antibody is supplied in PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,4 °C
- Stockage commentaire
- IRF7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Antigène
- IRF7 (Interferon Regulatory Factor 7 (IRF7))
- Autre désignation
- IRF7 (IRF7 Produits)
- Synonymes
- anticorps wu:fl24c03, anticorps zgc:66043, anticorps zgc:77947, anticorps IRF7, anticorps irf7, anticorps IRF-7H, anticorps IRF7A, anticorps IRF7B, anticorps IRF7C, anticorps IRF7H, anticorps interferon regulatory factor 7, anticorps irf7, anticorps IRF7, anticorps Irf7
- Sujet
- IRF7 Antibody: Interferons (IFNs) are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms. During infection, host-virus interactions signal downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-alpha/beta genes. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. IRF7 play a major role in the innate immune pathway, interacting with the Toll-like receptor (TLR) adaptor proteins MyD88 and Tirp/TRAM and functioning as an intermediate TLR4 and TLR9 signaling. There are at least four differentially spliced isoforms of IRF7, although their function has not been clearly established.
- ID gène
- 3665
- UniProt
- Q92985
- Pathways
- Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Autophagy
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