SH3BP4 anticorps (C-Term)

N° du produit ABIN6991118

L’anticorps Lapin Polyclonal anti-SH3BP4 a été validé pour WB, ELISA et IHC (p). Il convient pour détecter SH3BP4 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SH3BP4 anticorps (C-Term) (ABIN6991118)

Antigène: SH3BP4 (SH3-Domain Binding Protein 4 (SH3BP4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SH3BP4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-SH3BP4 anticorps

Épitope: AA 860-910, C-Term

Purification: SH3BP4 Antibody is affinity chromatography purified via peptide column.

Immunogène: SH3BP4 antibody was raised against an 18 amino acid synthetic peptide from near the carboxy terminus of human SH3BP4. The immunogen is located within amino acids 860 - 910 of SH3BP4.

Isotype: IgG

Information d'application

Indications d'application: SH3BP4 antibody can be used for detection of SH3BP4 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in rat samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: SH3BP4 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: SH3BP4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur SH3BP4

Antigène: SH3BP4 (SH3-Domain Binding Protein 4 (SH3BP4))

Autre désignation: SH3BP4

Sujet: SH3BP4 Antibody: SH3BP4 was initially isolated as a novel cDNA using differential display analysis using cultured human corneal fibroblasts. The protein contains three Asn-Pro-Phe (NPF) motifs, an SH3 domain, a PXXP motif, a bipartite nuclear targeting signal, and a tyrosine phosphorylation site. SH3BP4 has been shown to interact with specific endocytic proteins such as clathrin, dynamin, and the transferrin receptor (TfR) and localizes to TfR-containing coated pits and vesicles. It is thought to be involved in cargo-specific control of clathrin-mediated endocytosis, specifically controlling the internalization of TfR. At least two isoforms of SH3BP4 are known to exist.

ID gène: 23677

NCBI Accession: NP_055336

UniProt: Q9P0V3