NLRX1 anticorps (N-Term)

N° du produit ABIN6991399

Cet anticorps Lapin Polyclonal détecte spécifiquement NLRX1 dans WB, ELISA, IF et IHC (p). Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour NLRX1 anticorps (N-Term) (ABIN6991399)

Antigène: NLRX1 (NLR Family Member X1 (NLRX1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRX1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-NLRX1 anticorps

Épitope: AA 70-120, N-Term

Purification: NOD5 Antibody is affinity chromatography purified via peptide column.

Immunogène: NOD5 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human NOD5. The immunogen is located within amino acids 70 - 120 of NOD5.

Isotype: IgG

Information d'application

Indications d'application: NOD5 antibody can be used for detection of NOD5 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: NOD5 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: NOD5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur NLRX1

Antigène: NLRX1 (NLR Family Member X1 (NLRX1))

Autre désignation: NOD5

Sujet: NOD5 Antibody: NOD5, also known as NLRX1, is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD5 localizes to the mitochondrial outer membrane and interacts with the virus-induced signaling adapter protein VISA. Unlike a subset of NOD-like receptors (NLRs) such as NOD1 and NOD2 which trigger pro-inflammatory cascades, and other NLRs that induce the caspase 1 inflammasome in response to immune challenges, NOD5 amplifies NF-κ,B and JNK pathways by inducing reactive oxygen species production.

ID gène: 79671

NCBI Accession: NP_078894

UniProt: Q86UT6

Pathways: SARS-CoV-2 Protein Interactome