CD33 anticorps (AA 180-230)

N° du produit ABIN6991611

Cet anticorps anti-CD33 est un anticorps Lapin Polyclonal détectant CD33 dans WB et ELISA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour CD33 anticorps (AA 180-230) (ABIN6991611)

Antigène: CD33

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD33 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CD33 anticorps

Épitope: AA 180-230

Specificité: At least three isoforms of CD33 are known to exist, this antibody will detect all three isoforms.

Purification: CD33 Antibody is affinity chromatography purified via peptide column.

Immunogène: CD33 antibody was raised against a 14 amino acid synthetic peptide near the center of human CD33. The immunogen is located within amino acids 180 - 230 of CD33.

Isotype: IgG

Information d'application

Indications d'application: CD33 antibody can be used for detection of CD33 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: CD33 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: CD33 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur CD33

Antigène: CD33

Autre désignation: CD33

Sujet: CD33 Antibody: CD33 is a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family that is highly expressed on myeloid progenitor cells. Assessment of CD33 expression is of great importance in the immunodiagnosis of acute leukemia, allowing distinction between myeloid and lymphoid origin, as CD33 is generally restricted to the myelomonocytic lineage. CD33 can associate with the protein-tyrosine phosphatases SHP-1 and SHP-2 and thus could modulate downstream signaling events associated with cell activation. Common variants of CD33 have been found to be associated with late-onset Alzheimer's disease.

ID gène: 945

NCBI Accession: NP_001763

UniProt: P20138