DISP1 anticorps (N-Term)

N° du produit ABIN6991624

Cet anticorps Lapin Polyclonal détecte spécifiquement DISP1 dans WB, ELISA, IF et IHC (p). Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour DISP1 anticorps (N-Term) (ABIN6991624)

Antigène: DISP1 (Dispatched Homolog 1 (DISP1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DISP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-DISP1 anticorps

Épitope: AA 20-70, N-Term

Specificité: At least two isoforms of DISP1 are known to exist, this antibody will detect both isoforms. DISP1 antibody is predicted to not cross-react with EMX1.

Purification: DISP1 Antibody is affinity chromatography purified via peptide column.

Immunogène: DISP1 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human DISP1. The immunogen is located within amino acids 20 - 70 of DISP1.

Isotype: IgG

Information d'application

Indications d'application: DISP1 antibody can be used for detection of DISP1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: DISP1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: DISP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur DISP1

Antigène: DISP1 (Dispatched Homolog 1 (DISP1))

Autre désignation: DISP1

Sujet: DISP1 Antibody: DISP1 is the mammalian homolog of the Drosophila Dispatched segment-polarity gene and a key regulator of the Hedgehog (Hh) signaling pathway during embryonic development. DISP1 is required to move Shh from site of synthesis during embryogenesis, mutations in the gene result in lethality at mid-gestation and prevents specification of ventral cell types in the neural tube. Recent results have shown that DISP1 mediates the basolateral secretion of Shh and regulates growth of mammalian long bones through the control of Ihh.

ID gène: 84976

NCBI Accession: NP_116279

UniProt: Q96F81

Pathways: Signalisation Hedgehog