TET3 anticorps (C-Term)

N° du produit ABIN6991743

Cet anticorps anti-TET3 est un anticorps Lapin Polyclonal détectant TET3 dans WB, ELISA, IF et IHC (p). Adapté pour Humain, Souris et Rat.

Aperçu rapide pour TET3 anticorps (C-Term) (ABIN6991743)

Antigène: TET3 (Tet Methylcytosine Dioxygenase 3 (TET3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TET3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-TET3 anticorps

Épitope: AA 1520-1570, C-Term

Specificité: At least three isoforms of TET3 are known to exist. TET3 antibody is predicted to not cross react with other TET proteins.

Purification: TET3 Antibody is affinity chromatography purified via peptide column.

Immunogène: TET3 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human TET3. The immunogen is located within amino acids 1520 - 1570 of TET3.

Isotype: IgG

Information d'application

Indications d'application: TET3 antibody can be used for detection of TET3 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: TET3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: TET3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur TET3

Antigène: TET3 (Tet Methylcytosine Dioxygenase 3 (TET3))

Autre désignation: TET3

Sujet: TET3 Antibody: TET3, a member of the ten-eleven-translocation (TET) family of genes, is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine and is most abundantly expressed in hematopoietic cells. Unlike the related TET2 protein, mutations in TET3 have not been observed in any myeloid malignancies. TET3 has been shown to be involved in the demethylation of zygotic DNA before the first mitosis and has been suggested to be involved in the epigenetic reprogramming of the zygotic paternal DNA following natural fertilization and may also contribute to somatic cell nuclear reprogramming during animal cloning.

Poids moléculaire: 183 kDa

ID gène: 200424

NCBI Accession: NP_001274420

UniProt: O43151

Pathways: L'effet Warburg