ATG14 anticorps (AA 270-320)

N° du produit ABIN6991757

L’anticorps anti-ATG14 Polyclonal Lapin est utilisé pour la détection de ATG14 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA et IF.

Aperçu rapide pour ATG14 anticorps (AA 270-320) (ABIN6991757)

Antigène: ATG14 (ATG14 Autophagy Related 14 (ATG14))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG14 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-ATG14 anticorps

Épitope: AA 270-320

Specificité: At least three isoforms of ATG14 are known to exist, this antibody will detect all three isoforms

Purification: ATG14 Antibody is affinity chromatography purified via peptide column.

Immunogène: ATG14 antibody was raised against an 18 amino acid synthetic peptide near the center of human ATG14. The immunogen is located within amino acids 270 - 320 of ATG14.

Isotype: IgG

Information d'application

Indications d'application: ATG14 antibody can be used for detection of ATG14 by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: ATG14 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: ATG14 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur ATG14

Antigène: ATG14 (ATG14 Autophagy Related 14 (ATG14))

Autre désignation: ATG14

Sujet: ATG14 Antibody: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein ATG1. ATG14 is a subunit of a class III phosphatidylinositol (PtdIns) 3-kinase complex that targets the complex to the endoplasmic reticulum, the site of autophagosome formation.

Poids moléculaire: 54 kDa

ID gène: 22863

NCBI Accession: NP_055739

UniProt: Q6ZNE5

Pathways: Autophagy